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05/2019-σήμερα Μεταδιδακτορική Έρευνα στην Επεμβατική Καρδιολογία “Αξιολόγηση της ασφάλειας και της αποτελεσματικότητας νεότερων τεχνικών αντιμετώπισης διχασμών στη σύγχρονη αγγειοπλαστική χρόνιων ολικών αποφράξεων των στεφανιαίων αγγείων ”Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης, Θεσσαλονίκη, Ελλάδα
12/2011-03/2019 Διδακτορικό Δίπλωμα στην Επεμβατική Καρδιολογία “Ο ρόλος των παλίνδρομων τεχνικών στη σύγχρονη αντιμετώπιση χρόνιων ολικών αποφράξεων των στεφανιαίων αγγείων.” Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης, Θεσσαλονίκη, Ελλάδα (Άριστα με διάκριση)
2008-2010 Μεταπτυχιακό Δίπλωμα Ειδίκευσης (Master in Science, MSc) “Ιατρική Ερευνητική Μεθοδολογία, Κατεύθυνση: Κλινική Έρευνα”. Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης, Θεσσαλονίκη, Ελλάδα (Άριστα, 9.47/10)
Ιούλιος 2005 Πτυχίο Ιατρικής
1999-2005 Ιατρική Σχολή Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης, Θεσσαλονίκη, Ελλάδα
Επαγγελματική Εμπειρία
01/01/2020- 31/12/2020 Εκπαίδευση στην Επεμβατική Καρδιολογία (Fellow in Interventional Cardiology) Institute Cardiovasculaire Paris Sud Massy, Paris, France Director: Bernard Chevalier, MD, FESC, FACC, FSCAI Head of Research, Director of the Fellowship Program
13/03/2019-31/12/2019 Καρδιολόγος Καρδιολογική Κλινική Κλινική Άγιος Λουκάς, Θεσσαλονίκη Διευθυντής: Δρ. Δημοσθένης Κατσάρκας
27/06/2018-12/03/2019 Καρδιολόγος Α’ Πανεπιστημιακή Καρδιολογική Κλινική Α.Π.Θ. Πανεπιστημιακό Νοσοκομείο ΑΧΕΠΑ, Θεσσαλονίκη Διευθυντής: Καθηγητής Χαράλαμπος Καρβούνης
14/04/2014-26/06/2018 Ειδικευόμενος Καρδιολογίας Α’ Πανεπιστημιακή Καρδιολογική Κλινική Α.Π.Θ. Πανεπιστημιακό Νοσοκομείο ΑΧΕΠΑ, Θεσσαλονίκη Διευθυντής: Καθηγητής Χαράλαμπος Καρβούνης
2013-2014 Επιστημονικός συνεργάτης, Κλινικός ερευνητής Royal Brompton Hospital Imperial College Λονδίνο, Μεγάλη Βρετανία Διευθυντής: Professor Carlo Di Mario
10/06/2011-2013 Επιστημονικός συνεργάτης, Κλινικός ερευνητής Α’ Πανεπιστημιακή Καρδιολογική Κλινική Α.Π.Θ. Πανεπιστημιακό Νοσοκομείο ΑΧΕΠΑ, Θεσσαλονίκη Διευθυντής: Καθηγητής Χαράλαμπος Καρβούνης
05/06/2009-22/02/2011 Ειδικευόμενος Παθολογίας Παθολογική Κλινική Γενικό Νοσοκομείο Νάουσας Νάουσα
30/04/2008-29/01/2009 Υπηρεσία Υπαίθρου Περιφερειακό Ιατρείο Δεσκάτης Γενικό Νοσοκομείο Γρεβενών, Γρεβενά
13/02/2006-13/02/2007 Ιατρός Υποχρεωτική Στρατιωτική Θητεία
Ερευνητικό Έργο, Δημοσιεύσεις
• Nikolaos V. Konstantinidis MD, MSc, PhD, Gerasimos Gogas MD, Efstratios Karagiannidis MD, MSc, Paraskevi Daskalaki, Athena Nasoufidou MD. The pathophysiology of coronary chronic total occlusions. Athirologia. Northern Greece Society of Atherosclerosis. 2020 December.
• Efstratios Karagiannidis, Nikolaos V. Konstantinidis, Georgios Sofidis, Evangelia Chatzinikolaou, Georgios Sianos. Rationale and design of a prospective, observational study for the QUantitative EStimation of Thrombus burden in patients with ST-Elevation Myocardial Infarction using micro-computed tomography: the QUEST-STEMI trial. BMC Cardiovasc Disord. 2020 Mar 11;20(1):125. doi: 10.1186/s12872-020-01393-5.
• Nikolaos V. Konstantinidis, Gerald S. Werner, Spyridon Deftereos, Carlo Di Mario Alfredo R. Galassi, Joachim H. Buettner, Alexandre Avran, Nicolaus Reifart Omer Goktekin, Roberto Garbo, Alexander Bufe, Kambis Mashayekhi, Nicolas Boudou, Markus Meyer - Geßner, Bernward Lauer, Simon Elhadad, Evald H. Christiansen, Javier Escaned, David Hildick-Smith, Mauro Carlino, Yves Louvard, Thierry Lefèvre, Georgios Giannopoulos, Georgios Sianos on behalf of the Euro CTO Club. Temporal Trends in Chronic Total Occlusion Interventions in Europe: 17,626 Procedures from the ERCTO Registry. Circ Cardiovasc Interv. 2018;11:e006229.
• Alfredo R Galassi MD, Gerald S Werner MD, PhD, Marouane Boukhris MD, Lorenzo Azzalini MD, PhD, MSc, Kambis Mashayekhi MD, Mauro Carlino MD, Alexandre Avran MD, Nikolaos V. Konstantinidis MD, MSc, Luca Grancini MD, Leszek Bryniarski MD, PhD, Roberto Garbo MD, Antony Gershlick MD, Carlo Di Mario MD, PhD, Nicolaus Reifart MD, PhD, Georgios Sianos MD, PhD; on behalf of the EuroCTO Club. Percutaneous Recanalization of Chronic Total Occlusions: 2019 Consensus Document from the EuroCTO Club. Eurointervention 2019; Jaa-510 2019, doi: 10.4244/EIJ-D-18-00826.
• Dimitrios Petroglou, MD, Matthaios Didagelos, MD, Georgios Chalikias, MD, PhD, Dimitrios Tziakas, MD, PhD, Grigorios Tsigkas, MD, PhD, Georgios Hahalis, MD, PhD, Michael Koutouzis, MD, Antonios Ntatsios, MD, Ioannis Tsiafoutis, MD, Michael Hamilos, MD, PhD, Antonios Kouparanis, MD, Nikolaos Konstantinidis, MD, Georgios Sofidis , MD, PhD, Samir B. Pancholy, MD, PhD, Haralambos Karvounis, MD, PhD, Olivier Bertrand, MD, PhD, Antonios Ziakas, MD, PhD. Manual vErsus Mechanical cOmpression of the Radial arterY after Transradial Coronary Angiography – the MEMORY Multicenter Randomized Trial. JACC Interventions, ahead of print.
• Nikolaos V. Konstantinidis, Georgios Sianos. Single guiding catheter retrograde CTO recanalization facilitated by trapping technique; introducing the Modified Rendezvous Technique EuroIntervention. 2017 Aug 22. pii: EIJ-D-17-00532. doi: 10.4244/EIJ-D-17-00532.
• Nikolaos V. Konstantinidis, Georgios Sofidis, Vasileios Kolettas, Haralambos Karvounis, Georgios Sianos. Bifurcation CTO recanalization with contemporary antegrade and retrograde techniques in a patient with two chronically occluded coronary arteries. Hellenic J Cardiol. 2016 Sep - Oct;57(5):371-374. doi: 10.1016/j.hjc.2016.11.029.
• Georgios Sianos, George Giannakoulas, Nikolaos V. Konstantinidis, Sophia Anastasia Mouratoglou, Vasileios Koletas, Georgios Sofidis, Apostolos Tzikas, Gregory Giamouzis, Haralambos Karvounis.A case of balloon pulmonary angioplasty as palliative therapy in chronic thromboembolic pulmonary hypertension. Hellenic J Cardiol. 2016 Sep -Oct;57(5):363-365. doi: 10.1016/j.hjc.2016.11.006.
• Georgios Sianos, Nikolaos V. Konstantinidis, Carlo Di Mario, Haralambos Karvounis. Theory and practical based approach to chronic total occlusions. BMC Cardiovascular Disorders 2016; 16 (33).
• Ismail Dogu Kilic, Nicolas Foin, Nikolaos Konstantinidis, Roberta Serdoz, Gianluca Caiazzo, Carlo Di Mario. Stent deformation at the edge of a high pressure balloon. Cardiovascular Revascularization Medicine 2015; 16 (8): 508-509.
• Ismail Dogu Kilic, Nikolaos Konstantinidis, Michele Pighi, Alessio Mattesini, Carlo Di Mario. Stop adding metal layers: Will bioabsorbable scaffolds become the gold standard for late in-stent restenosis and neo-atherosclerosis? Cardiovascular Revascularization Medicine 2015; 16 (2): 124-126.
• Ismail Dogu Kilic, Nikolaos Konstantinidis, Gianluca Caiazzo, Enrico Fabris, Sara S.S.M. Abou Sherif, Carlo Di Mario. Influence of multimodality coronary imaging on revascularization strategy. International Journal of Cardiology 2014; 177 (2): 515–516.
• Mattesini, A., Pighi, M., Konstantinidis, N., Ghione, M., Kilic, D., Foin, N., Dall'Ara, G., Secco, G.G., Valente, S., Di Mario, C. Optical coherence tomography in bioabsorbable stents: Mechanism of vascular response and guidance of stent implantation. Minerva Cardioangiologica 2014; 62 (1): 71-82.
• Kilic, I.D., Konstantinidis, N., Pighi, M., Serdoz, R., Di Mario, C. NIRS-IVUS-guided implantation of pericardium-covered stents in a giant coronary aneurysm. European Heart Journal Cardiovascular Imaging. 2014; 15 (9): 1061.
• Nikolaos Konstantinidis, Michele Pighi, Ismail Dogu Kilic, Roberta Serdoz, Georgios Sianos, Carlo Di Mario. New advances in Chronic Total Occlusions. Interv Cardiol. 2014 Aug; 9(3): 208–212.
• Konstantinidis Nikolaos, Sianos Georgios. Tools and techniques: CTO-the retrograde approach. Eurointervention; Tools and Techniques, 2013.
• Konstantinidis Nikolaos, Sianos Georgios. Double Chronic Total Occlusion Recanalisation with Antegrade and Retrograde Techniques and the Use of a Novel Drug-eluting Stent with Biodegradable Polymer. Interventional Cardiology Review, 2013;8(1):46–9.
• Sianos G, Werner GS, Galassi AR, Papafaklis MI, Escaned J, Hildick-Smith D, Christiansen EH, Gershlick A, Carlino M, Karlas A, Konstantinidis NV, Tomasello SD, Di Mario C, Reifart N. Recanalisation of chronic total coronary occlusions: 2012 consensus document from the eurocto club. EuroIntervention. 2012;8:139-145.
• Konstantinidis Nikolaos, Sianos Georgios. Post-coronary Artery Bypass Grafting –Degenerated Saphenous Vein Graft Intervention, or Native Vessel Coronary Chronic Total Occlusion Recanalisation? Interventional Cardiology, 2012;7(1):66–70.
Ερευνητικό Έργο, Συμμετοχή σε Διεθνή Συνέδρια
• N. Konstantinidis. Retrograde Approach in the Treatment of Coronary Chronic Total Occlusion; Results from a Northern Greek Center of Reference. 18 Panhellenic Congress in Cardiology, North Hellenic Society of Cardiology, 16-18 May 2019, Thessaloniki, Greece
• N. Konstantinidis. Temporal Trends in Chronic Total Occlusion Percutaneous Recanalization in A Northern Greek Center Of Reference. 18 Panhellenic Congress in Cardiology, North Hellenic Society of Cardiology, 16-18 May 2019, Thessaloniki, Greece
• N. Konstantinidis. Beware of your wire! Coronary perforation during CTO PCI. New Trends in Cardiology, 1-2 March 2019, Thessaloniki, Greece
• N. Konstantinidis. Case presentation. Retrograde CTO approach. Triple retrograde access to facilitate crux bifurcation treatment of a chronically occluded right coronary artery. EuroPCR 2018, 22-25 May, 2018, Paris, France.
• N. Konstantinidis. Interventricular Septal Hematoma and aortocoronary dissection following retrograde CTO RCA recanalization. New Trends in Cardiology, 12-13 January 2018, Thessaloniki, Greece
• N. Konstantinidis. Acute Coronary Syndromes. National Emergency Aid Center; 22ndPostgraduate Medical Training Program in Emergency Medicine. 3 November 2017, Thessaloniki, Greece
• N. Konstantinidis. Case presentation. CTO Innovative approach. Guide extension facilitated reverse controlled antegrade retrograde dissection reentry technique for the treatment of a bifurcation CTO in a patient post coronary artery bypass grafting. EuroPCR 2017, 16-19 May, 2017, Paris, France.
• N. Konstantinidis. Case presentation. CTO Innovative approach. Tandem bifurcation CTO of left anterior descending artery in a patientpost-coronary artery bypass grafting treated with double retrograde access. EuroPCR 2017, 16-19 May, 2017, Paris, France.
• N. Konstantinidis. Case presentation. CTO Innovative approach. Modified "Rendez-vouz technique" for CTO recanalization; single guiding catheter retrograde CTO recanalization facilitated by trapping technique inside a 5 French guide extension catheter. EuroPCR 2017, 16-19 May, 2017, Paris, France.
• N. Konstantinidis. Case presentation. Bifurcation CTO treated with contemporary antegrade and retrograde techniques. Joint Interventional Meeting (JIM) 2017, 9-11 February 2017, Milan, Italy
• N. Konstantinidis. Rationale for CTO Recanalization. Sixth Bulgarian Bifurcation and Complex Coronary Interventions Course. 20-22 January 2017, Tokuda Hospital, Sofia
• N. Konstantinidis. Antegrade treatment of bifurcation CTO. The Experts Live Workshop 2016, The EuroCTO Club Meeting, 30th September-1st October 2016, Krakow, Poland
• G. Giannopoulos, N. Konstantinidis, A. Galassi, G.S. Werner, C. Di Mario, J. Escaned, J.H. Buettner, E.H. Christiansen, D. Hildick¬Smith, M. Carlino, Y. Louvard , T. Lefevre , N. Reifart , S. Deftereos, G. Sianos. Poster session 7: Challenges with total chronic occlusions. Temporal trends in chronic total occlusion interventions in Europe: 17,626 procedures from the ercto registry. European Society Association (ESC) Congress 2016, 27-31 August 2016, Rome, Italy.
• Deftereos, N. Konstantinidis, G. Giannopoulos, A. Galassi, G.S. Werner, C. Di Mario, J. Escaned, J.H. Buettner, E.H. Christiansen, D. Hildick¬Smith, M. Carlino, Y. Louvard, T. Lefevre, N. Reifart, G. Sianos. Poster session 7: Challenges with total chronic occlusions. The J-CTO score as a predictor of procedural failure in chronic total occlusion interventions; Insights from the ERCTO Registry. European Society Association (ESC) Congress 2016, 27-31 August 2016, Rome, Italy.
• N. Konstantinidis. Cyprus, Greece and the United Kingdom share their most educational cases: complications during coronary intervention: if they cannot be avoided, how should they be treated? Epicardial channel perforation during the retrograde approach. EuroPCR 2016, 17-20 May, 2016, Paris, France.
• N. Konstantinidis. Bifurcation CTO RCA recanalization. New Trends in Cardiology, 14-16 April 2016, Thessaloniki, Greece
• N. Konstantinidis. Coronary angiography, coronary anatomy, anatomic variants, angiographic views and interpretation of collected data. Innovations in Interventional Cardiology and Electrophysiology, Thessaloniki, 10-12 September 2015
• N. Konstantinidis. Retrograde CTO Recanalization. Working Group on Interventional Cardiology of the Hellenic Society of Cardiology; Panhellenic Working Groups Meeting, 26-28 February 2015, Ioannina, Greece
• N. Konstantinidis. Retrograde CTO Recanalization. Cases presentations. Working Group on Interventional Cardiology of the Hellenic Society of Cardiology; ICE 2014, 12-13 December 2014, Ioannina, Greece
• N. Konstantinidis, C. Di Mario. Indications to PCI; The special case of CTO Recanalization; Cases presentation. 13 March 2014, London, United Kingdom
• Carlo Di Mario, Ismail Dogu Killic, Michele Pighi, N. Konstantinidis. Rapid Review of the current CTO literature. CTO/LM Course, 27 February-1st March 2014, New York, USA
• N. Konstantinidis. Panel Commentator. LIVE CTO Cases. 20-21 September 2013, Szeged, Hungary
• N. Konstantinidis. Chronic total occlusions: indications and techniques. Case Presentation. Working Group on Interventional Cardiology of the Hellenic Society of Cardiology; ICE 2012, 14-15 December 2012, Ioannina, Greece
• G.Sianos, N. Konstantinidis, A. Karlas. Challenging Case Session I: Best Cases: LAD to LAD Retrograde Chronic Total Occlusion Recanalization via an Intraseptal Loop. Transcatheter Cardiovascular Therapeutics (TCT) 2012, 22-26 October 2012, Miami USA
• K.Kontotasios, D.Grammeniatis, N. Konstantinidis, S.Zoutis, A.Taplidis Interesting Case Session. Eosinophilic gastroenteritis. 25th North Hellenic Medical Conference, 18-20March 2010 Thessaloniki, Greece.
Ερευνητικό Έργο, Συγγραφικό Έργο
• Ν. Β. Κωνσταντινίδης, Α. Μαυρογιάννη, Γ.Χ. Μπομπότης, Γ.Σιάνος. Χρόνιες Ολικές Αποφράξεις. Βιβλίο Αιμοδυναμικής και Επεμβατικής Καρδιολογιας. Ομάδα Εργασίας Αιμοδυναμικής Καρδιολογίας, Ελληνική Καρδιολογική Εταιρεία, 2013
• Carlo Di Mario, Nikolaos Konstantinidis. Advances in the treatment of coronary chronic total occlusion. Braunwald’s Heart Disease, 2014
Κριτής σε Διεθνή Περιοδικά
• International Journal of Cardiology (Impact Factor 2019: 4.034)
Υποτροφίες, Διακρίσεις σε Διεθνή Συνέδρια
• 1ο Βραβείο Ερευνητικής Εργασίας (συνδυαστικά στις παρακάτω εργασίες)18ο Πανελλήνιο Καρδιολογικό Συνέδριο της Καρδιολογικής Εταιρείας Βορείου Ελλάδας, 16-18 Μαΐου 2019, Θεσσαλονίκη, Ελλάδαv Retrograde Approach in the Treatment of Coronary Chronic Total Occlusion; Results from a Northern Greek Center of ReferenceN. Konstantinidis, E. Karagiannidis, G. Sofidis, P. Daskalaki, M. Meletidou, G. Sianosv Temporal Trends in Chronic Total Occlusion Percutaneous Recanalization in A Northern Greek Center Of Reference N. Konstantinidis, E. Karagiannidis, G. Sofidis, P. Daskalaki, M. Meletidou, G. Sianos
• 2ο Βραβείο Ερευνητικής Εργασίας 18ο Πανελλήνιο Καρδιολογικό Συνέδριο της Καρδιολογικής Εταιρείας Βορείου Ελλάδας, 16-18 Μαΐου 2019, Θεσσαλονίκη, Ελλάδαv Ποσοτική Μέτρηση Όγκου και Πυκνότητας Θρομβωτικού Υλικού με τη Χρήση Μικροτομογραφίας σε Ασθενείς με STEMI που Υποβάλλονται σε ΠρωτογενήΑγγειοπλαστική και Θρομβοαναρρόφηση Ε. Καραγιαννίδης, Ν. Κωνσταντινίδης, Γ. Σοφίδης, Ε. Χατζηνικολάου, Π. Δασκαλάκη, Μ. Μελετίδου, Γ. Σιάνος
• Ερευνητική Υποτροφία Εξωτερικού, Ελληνική Καρδιολογική Εταιρεία, 2012
• Ερευνητική Υποτροφία, απονεμήθηκε για την ολοκλήρωση του ερευνητικού προγράμματος: ““Ο ρόλος των παλίνδρομων τεχνικών στην αντιμετώπιση χρόνιων ολικών αποφράξεων των στεφανιαίων αγγείων.” Ελληνική Καρδιολογική Εταιρεία, 2012
Ερευνητικό Έργο, Συμμετοχή σε Κλινικές Μελέτες
• 2018: Quantitative Estimation of Thrombus Burden in Patients With STEMI Using Micro - Computed Tomography (QUEST-STEMI) ClinicalTrials.gov Identifier: NCT03429608
• 2017: GEnetic Syntax Score (GESS) Trial- ClinicalTrials.gov ID NCT03150680
• 2017: Correlation of clinical presentation and complexity of coronary artery disease with the metabolic profile of patients - CorLipid Trial
• 2016: A Prospective, Two-center Registry, Non-Randomized trial for evaluation of safety and feasibility of thromboaspiration via Guidion guide extension catheter in the context of ST elevation myocardial infarction with large thrombus burden.
Πιστοποιήσεις για Συμμετοχή σε Κλινικές Μελέτες
• Introduction to Good Clinical Practice (GCP) e-learning course. A practical guide to ethical and scientific quality standards in clinical research (2014)(Modules completed: Introduction to Research in the NHS Good Clinical Practice and Standards in Research Study Set-up and Responsibilities, The Process of Informed Consent Data Collection and Documentation, Safety Reporting)
• NIDA Clinical Trials Network, Good Clinical Practice (2017)(Modules completed: Institutional Review Boards, Informed Consent, Confidentiality & Privacy, Participant Safety & Adverse Events, Quality Assurance, The Research Protocol, Documentation & Record-Keeping, Research Misconduct, Roles & Responsibilities, Recruitment & Retention, Investigational New Drugs)
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